Manteau, Baptiste; Genix, Pierre; Brelot, Lydia; Vors, Jean-Pierre; Pazenok, Sergiy; Giornal, Florence; Leuenberger, Charlotte; Leroux, Frederic R. published the artcile< A General Approach to (Trifluoromethoxy)pyridines: first X-ray Structure Determinations and Quantum Chemistry Studies>, Reference of 73018-09-4, the main research area is general approach synthesis Trifluoromethoxy pyridines crystal structure; ab initio energy profiles rotation trifluoromethoxy methoxy pyridines.
The previously unknown 2-, 3-, and 4-(trifluoromethoxy)pyridines have now become readily accessible by means of an efficient and straightforward large-scale synthesis. Their regioselective functionalization by organometallic methods has been studied and has afforded new and highly important building blocks for life-sciences-oriented research. In addition, the first X-ray crystallog. structure determinations of (trifluoromethoxy)pyridines have been performed. Lowest-energy conformations of (trifluoromethoxy)pyridines and (trifluoromethoxy)pyridinium cations were determined by in silico studies.
European Journal of Organic Chemistry published new progress about Anomeric effect. 73018-09-4 belongs to class pyridine-derivatives, and the molecular formula is C5H4ClNO, Reference of 73018-09-4.