Manteau, Baptiste’s team published research in European Journal of Organic Chemistry in 2010 | CAS: 1221171-81-8

3-(Trifluoromethoxy)picolinic acid(cas: 1221171-81-8) belongs to pyridine. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. As ligands, solvents, and catalysts they facilitate reactions; thus descriptions of these new ligands and their applications abound each year.COA of Formula: C7H4F3NO3

COA of Formula: C7H4F3NO3On November 30, 2010 ,《A General Approach to (Trifluoromethoxy)pyridines: first X-ray Structure Determinations and Quantum Chemistry Studies》 appeared in European Journal of Organic Chemistry. The author of the article were Manteau, Baptiste; Genix, Pierre; Brelot, Lydia; Vors, Jean-Pierre; Pazenok, Sergiy; Giornal, Florence; Leuenberger, Charlotte; Leroux, Frederic R.. The article conveys some information:

The previously unknown 2-, 3-, and 4-(trifluoromethoxy)pyridines have now become readily accessible by means of an efficient and straightforward large-scale synthesis. Their regioselective functionalization by organometallic methods has been studied and has afforded new and highly important building blocks for life-sciences-oriented research. In addition, the first X-ray crystallog. structure determinations of (trifluoromethoxy)pyridines have been performed. Lowest-energy conformations of (trifluoromethoxy)pyridines and (trifluoromethoxy)pyridinium cations were determined by in silico studies.3-(Trifluoromethoxy)picolinic acid(cas: 1221171-81-8COA of Formula: C7H4F3NO3) was used in this study.

3-(Trifluoromethoxy)picolinic acid(cas: 1221171-81-8) belongs to pyridine. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. As ligands, solvents, and catalysts they facilitate reactions; thus descriptions of these new ligands and their applications abound each year.COA of Formula: C7H4F3NO3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem