Matsuoka, Keitaro; Komami, Narumi; Kojima, Masahiro; Mita, Tsuyoshi; Suzuki, Kimichi; Maeda, Satoshi; Yoshino, Tatsuhiko; Matsunaga, Shigeki published their research in Journal of the American Chemical Society in 2021. The article was titled 《Chemoselective Cleavage of Si-C(sp3) Bonds in Unactivated Tetraalkylsilanes Using Iodine Tris(trifluoroacetate)》.Formula: C7H9NO The article contains the following contents:
Herein chemoselective cleavage of Si-C(sp3) bonds of unactivated tetraalkylsilanes was reported using iodine tris(trifluoroacetate). The reaction proceeded smoothly under mild conditions (-50°C to room temperature) and tolerated various polar functional groups, thus enabling subsequent Tamao-Fleming oxidation to provide the corresponding alcs. NMR experiments and d. functional theory calculations on the reaction indicated that the transfer of alkyl groups from Si to the I(III) center and the formation of the Si-O bond proceed concertedly to afford an alkyl-λ3-iodane and silyl trifluoroacetate. The developed method enabled the use of unactivated tetraalkylsilanes as highly stable synthetic precursors. In the part of experimental materials, we found many familiar compounds, such as 2-(2-Hydroxyethyl)pyridine(cas: 103-74-2Formula: C7H9NO)
2-(2-Hydroxyethyl)pyridine(cas: 103-74-2) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.Formula: C7H9NO