Mayer, Joachim M. published the artcileDeviations in the log P (partition coefficient) of protonated arylalkylamines and in their apparent log P, COA of Formula: C7H11ClN2, the main research area is amine aryl protonated partition coefficient; pyridylamine partition coefficient; phenylalkylamine partition coefficient.
Partition coefficients of monoprotonated phenyl- and 2-, 3-, and 4-pyridyl-substituted alkylamines show unpredictable but consistent trends. The coefficients of the Me, Bu, and pentyl homologs in each series are linearly related, while the Et and Pr derivatives appear too lipophilic. Thus, these partition coefficients are affected by perturbative effects, e.g., hydration or ion pairing. Also, the phosphate buffers yield abnormally low partition coefficient values.
European Journal of Medicinal Chemistry published new progress about Additivity. 84359-16-0 belongs to class pyridine-derivatives, name is 2-(Pyridin-3-yl)ethanamine hydrochloride, and the molecular formula is C7H11ClN2, COA of Formula: C7H11ClN2.