On November 30, 1982, McPheat, W. L.; Wardlaw, A. C. published an article.Related Products of 636-73-7 The title of the article was Inhibition of nicotinic acid and nicotinamide uptake into Bordetella pertussis by structural analogs. And the article contained the following:
The nicotinic acid (I) and nicotinamide (II) structural analogs, 3-pyridinecarboxaldehyde (III) and 3-pyridinealdoxime (IV) (both 500 and 50 μM), but not isonicotinamide, isonicotinic acid, 6-aminonicotinic acid, 6-aminonicotinamide, isoniazid, 3-acetylpyridine, 3-pyridylacetic acid, N,N-diethylnicotinamide, or 3-pyridinesulfonic acid, were effective and specific inhibitors of the uptake of I and II by B. pertussis, although neither compound inhibited the growth of the bacteria in liquid medium or the oxidation of glutamate by washed suspensions. 3-Pyridylcarbinol, at the same dose, was inhibitory, but less so than III and IV. The experimental process involved the reaction of Pyridine-3-sulfonic acid(cas: 636-73-7).Related Products of 636-73-7
The Article related to nicotinate nicotinamide transport metabolism bordetella, pyridinecarboxaldehyde bordetella nicotinamide uptake inhibition, pyridinealdoxime bordetella nicotinamide uptake inhibition and other aspects.Related Products of 636-73-7