Measurement and correlation on solubility of acetaminophen in aqueous solutions of 1-octyl-3-methyl imidazolium bromide, 1-butyl-4-methyl pyridinium bromide and 1-octyl-4-methyl pyridinium bromide was written by Mehrdad, Abbas;Taeb, Sara;Ehsani-Tabar, Sahar;Hossein Miri, Amir. And the article was included in Journal of Chemical Thermodynamics in 2020.Electric Literature of C10H16BrN This article mentions the following:
Aqueous solubility of acetaminophen in the presence of 1-octyl-3-Me imidazolium bromide, 1-butyl-4-Me pyridinium bromide and 1-octyl-4-Me pyridinium bromide ionic liquid, as co-solvent was investigated at different temperatures and mass fraction of ionic liquid The obtained results reveal that the solubility of acetaminophen was increased by increasing temperature and concentration of ionic liquid Solubility of ACP was significantly increased when mass fraction of 1-octyl-3-Me imidazolium bromide and 1-octyl-4-Me pyridinium bromide reaches to more than 0.05. The possible reasons behind enhanced solubility of ACP in aqueous solution of ionic liquid are hydrophobic interaction and the formed micelles by cations of ionic liquid Thermodn. functions of dissolution were calculated by Van’t Hoff equation. The exptl. solubility of acetaminophen was correlated with the modified Wilson and the electrolyte-NRTL models as activity coefficient model. In the experiment, the researchers used many compounds, for example, 1-Butyl-4-methylpyridin-1-ium bromide (cas: 65350-59-6Electric Literature of C10H16BrN).
1-Butyl-4-methylpyridin-1-ium bromide (cas: 65350-59-6) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Electric Literature of C10H16BrN