Meng, Fei published the artcile< Aggregation induced emission-active molecules bearing tunable singlet oxygen generation: The different length alkyl chain matters>, Electric Literature of 350-03-8, the main research area is AIE PDT photosensitizer prepnh singlet oxygen cancer; Aggregation induced emission; Alkyl chain; Molecular design strategy; Tunable (1)O(2) yield.
The efficiency of singlet oxygen (1O2) can be subtly regulated by mol. alkyl chain length according to ΔEST (the energy gap between S1 and T1 states). Which offer a strategy to adjust the 1O2 yield of photosensitizers (PSs) by mol. design strategy. Herein, three PSs (MZ1 ∼ MZ3) were constructed of β-terpyridine derivatives, which possess different length alkyl chain (Bu, hexyl, and octyl group) with tunable 1O2 yield (3.366, 2.461 and 0.963). Based on studies that PSs with aggregation induced emission (AIE) characteristics showed effective emission intensity and high 1O2 yield. Subsequently, Photodynamic therapy (PDT) in vitro was further investigated. MZ1 showed relatively highest 1O2 yield, considerable cellular uptake and effective cell apoptosis upon light irradiation
Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy published new progress about Aggregation-induced emission. 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Electric Literature of 350-03-8.