Mikle, Gabor; Bede, Fanni; Kollar, Laszlo published the artcile< Synthesis of N-picolylcarboxamides in aminocarbonylation>, Quality Control of 3731-53-1, the main research area is picolylcarboxamide preparation; iodocamphene steroidal iodoalkene picolylamine aminocarbonylation palladium catalyst.
Palladium-catalyzed aminocarbonylation of iodocamphene and steroidal iodoalkenes was carried out in the presence of 2-, 3- and 4-picolylamine, as well as secondary amines possessing 1-picolyl substituent. In general, primary picolylamines require less than 2 h to achieve practically complete conversion. The secondary amines proved to be less reactive, requiring 6-24 h depending on the substrate structure. The corresponding carboxamides were isolated in moderate to excellent yields. The synthesis of α,β-unsaturated carboxamides is based on the synthesis of iodoalkene substrates from enolizable ketones.
Tetrahedron published new progress about Amides Role: SPN (Synthetic Preparation), PREP (Preparation). 3731-53-1 belongs to class pyridine-derivatives, and the molecular formula is C6H8N2, Quality Control of 3731-53-1.