Murugesan, Kathiravan; Beller, Matthias; Jagadeesh, Rajenahally V. published the artcile< Reusable Nickel Nanoparticles-Catalyzed Reductive Amination for Selective Synthesis of Primary Amines>, Synthetic Route of 350-03-8, the main research area is primary amine preparation nickel nanoparticle catalyst; carbonyl compound ammonia mol hydrogen reductive amination; ammonia; carbonyl compounds; nickel nanoparticles; primary amines; reductive amination.
The preparation of nickel nanoparticles as efficient reductive amination catalysts by pyrolysis of in situ generated Ni-tartaric acid complex on silica is presented. The resulting stable and reusable Ni-nanocatalyst enables the synthesis of functionalized and structurally diverse primary benzylic, heterocyclic and aliphatic amines starting from inexpensive and readily available carbonyl compounds and ammonia in presence of mol. hydrogen. Applying this Ni-based amination protocol, -NH2 moiety can be introduced in structurally complex compounds, for example, steroid derivatives and pharmaceuticals.
Angewandte Chemie, International Edition published new progress about Carbonyl compounds (organic) Role: RCT (Reactant), RACT (Reactant or Reagent). 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Synthetic Route of 350-03-8.