Ruthenium(II)-catalyzed ortho-C-H arylation of diverse N-heterocycles with aryl silanes by exploiting solvent-controlled N-coordination was written by Nareddy, Pradeep;Jordan, Frank;Szostak, Michal. And the article was included in Organic & Biomolecular Chemistry in 2017.Formula: C12H11N This article mentions the following:
The first method for the direct, regioselective Ru(II)-catalyzed oxidative arylation of C-H bonds in diverse N-heterocycles, e.g., 1-phenyl-1H-pyrazole with aryl silanes 4-RC6H4Si(OMe)3 (R = H, Me, Cl, etc.) by exploiting solvent-controlled N-coordination has been reported. The reaction takes advantage of the attractive features of organosilanes as coupling partners, providing proof of concept for N-directed Ru(II)-catalyzed C-H arylation. This novel, operationally-simple and versatile protocol utilizes the Ru(II)/CuF2 reagent system in which CuF2 serves as a dual activator/oxidant in non-coordinating solvents to accommodate for ligand N-coordination. This first Ru(II)-catalyzed N-directed Hiyama C-H arylation offers broad implications to achieve numerous C-H bond functionalizations by versatile ruthenium(II) catalysis manifold. In the experiment, the researchers used many compounds, for example, 2-(m-Tolyl)pyridine (cas: 4373-61-9Formula: C12H11N).
2-(m-Tolyl)pyridine (cas: 4373-61-9) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the 锜?bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the 锜?bonds. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Formula: C12H11N