Ionic Liquids Mediated One-Pot Synthesis of Second Generation 5-Ethoxymethylfurfural (5-EMF); A Potent Biofuel Candidate was written by Naz, Sadia;Uroos, Maliha. And the article was included in ChemistrySelect in 2022.SDS of cas: 125652-55-3 This article mentions the following:
5-Ethoxymethylfurfural (5-EMF) is a promising fuel alternative and biofuel additive due to its high energy potential. Principal method for its synthesis is etherification of hydroxyl group of 5-hydroxymethylfurfural (5-HMF), produced by the dehydration of fructose. Currently existing methods for the synthesis of 5-EMF are not industrially feasible due to the issues associated with their starting materials; either they are highly expensive (such as 5-HMF), or compete with food (sugars such as fructose and glucose). Herein, we are reporting a one-pot protocol for the synthesis of 5-EMF using non-food indigenous agricultural waste material, thus completely eliminating the both issues. Cost is also very much reduced due to the utilization of cheap pyridinium based ionic liquids Energy, time and solvents use is also reduced, as reaction is happening in a single pot. The process is optimized first for fructose (73% 5-EMF yield) and glucose (16% 5-EMF), and was then extended for real biopolymeric cellulose (16% 5-EMF) and wheat husk biomass (15% 5-EMF). Product was characterized via HPLC and 1HNMR spectroscopy. In the experiment, the researchers used many compounds, for example, 1-Butyl-3-methylpyridinium Chloride (cas: 125652-55-3SDS of cas: 125652-55-3).
1-Butyl-3-methylpyridinium Chloride (cas: 125652-55-3) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the π-bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the σ bonds. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.SDS of cas: 125652-55-3