Synthetic Route of 72830-09-2, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C–H bond functionalisation has revolutionised modern synthetic chemistry. 72830-09-2, Name is 2-Chloromethyl-3,4-dimethoxypyridinium chloride, SMILES is COC1=C(OC)C(CCl)=NC=C1.[H]Cl, belongs to pyridine-derivatives compound. In a article, author is Werth, Jacob, introduce new discover of the category.
Cobalt Catalyzed Reductive Spirocyclopropanation Reactions
Cobalt pyridine-diimine (PDI) complexes catalyze the reductive spirocyclopropanation of terminal 1,3-dienes. gem-Dichlorocycloalkanes serve as carbene precursors and Zn is used as a terminal electron source. The reaction is effective for a range of gem-dichloro partners including those containing sulfur and nitrogen heterocycles. An example of an intramolecular Rh-catalyzed [5+2]-cycloaddition of a vinyl spirocyclopropane is demonstrated, providing rapid access to a complex tricyclic framework. Overall, this catalyst system is capable of suppressing the kinetically facile 1,2-hydride shift, which has hampered the development of Simmons-Smith reactions using Zn carbenoids possessing beta-hydrogen atoms.
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Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem