The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 5-(di-tert-Butylphosphino)-1′,3′,5′-triphenyl-1’H-1,4′-bipyrazole( cas:894086-00-1 ) is researched.Category: pyridine-derivatives.Lee, Daiki; Kondo, Hiroki; Kuwayama, Yui; Takahashi, Kento; Arima, Shiho; Omura, Satoshi; Ohtawa, Masaki; Nagamitsu, Tohru published the article 《Total synthesis of 4-epi-atpenin A5 as a potent nematode complex II inhibitor》 about this compound( cas:894086-00-1 ) in Tetrahedron. Keywords: atpenin A5 epi total synthesis hydroxylation palladium catalyst. Let’s learn more about this compound (cas:894086-00-1).
It is clear that atpenins and their analogs are useful chem. tools for elucidation of complex II functionality and that they could act as lead compounds for the development of novel helminth complex II-specific inhibitors. Recently, we discovered 4-epi-atpenin A5 (I) as a potent nematode complex II inhibitor during our SAR studies of atpenin A5. This result led us to embark on a concise total synthesis of 4-epi-atpenin A5. In this study, we describe the total synthesis of 4-epi-atpenin A5. Importantly, this was more concise and practical synthesis than our previous total synthesis of atpenin A5.
In some applications, this compound(894086-00-1)Category: pyridine-derivatives is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.