Adding a certain compound to certain chemical reactions, such as: 145100-50-1, 1,1,1-Trifluoro-N-(pyridin-2-yl)-N-((trifluoromethyl)sulfonyl)methanesulfonamide, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 145100-50-1, blongs to pyridine-derivatives compound. 145100-50-1
General procedure: Either (2S)-13 or (2R)-13 was dissolved in anhydrous DCM, and1.5 equivalents of 2-Pyridyltriflimide were added. The flask was placedunder N2 atmosphere and cooled to -78 C. 3.0 equivalents of N,Ndiisopropylethylaminewere added and the reaction slowly warmed toroom temperature and stirred for 20 h. Saturated aqueous ammoniumchloride was added, and extraction done with DCM. Organic fractionswere dried over sodium sulfate and purification was done by flashchromatography 98:2 (DCM:MeOH). TLC eluents used (95:5Dichloromethane: MeOH).
With the rapid development of chemical substances, we look forward to future research findings about 145100-50-1.
Reference:
Article; Perry, Charles K.; Casey, Austen B.; Felsing, Daniel E.; Vemula, Rajender; Zaka, Mehreen; Herrington, Noah B.; Cui, Meng; Kellogg, Glen E.; Canal, Clinton E.; Booth, Raymond G.; Bioorganic and Medicinal Chemistry; vol. 28; 3; (2020);,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem