The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 159307-02-5, name is 6-Acetylpicolinonitrile. This compound has unique chemical properties. The synthetic route is as follows. COA of Formula: C8H6N2O
Step c. To a solution of 6-acetylpicolinonitrile (0.1 g, 0.68 mmol) in acetic acid (10 ml) was added bromine (0.108 g, 0.68 mmol) in glacial acetic acid (5 ml) drop wise at 15C. The reaction mixture was stirred at rt for 20 h. The resulting reaction mixture was poured into saturated NaHC03 solution (30 ml) and neutralized with slow addition of solid Na2C03. The obtained mixture was extracted with EtOAc (3 x 40 ml). The combined organic phase was dried over Na2S04, filtered and concentrated under reduced pressure yielding 6-(2-bromoacetyl)picolinonitrile (0.4 g, 1.77 mmol). MS: ES+ 224.7; 226.7.
With the rapid development of chemical substances, we look forward to future research findings about 159307-02-5.
Reference:
Patent; MISSION THERAPEUTICS LIMITED; KEMP, Mark; STOCKLEY, Martin; JONES, Alison; (138 pag.)WO2017/9650; (2017); A1;,
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