Electric Literature of 19621-92-2 ,Some common heterocyclic compound, 19621-92-2, molecular formula is C6H5NO3, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
General procedure: The complex [RuH(CO)(6-OH-py-2-COO)(PPh3)2] (1) was synthesized by the reaction between [RuHCl(CO)(PPh3)3] (0.2 g, 2.0 × 10-4 mol) and 6-hydroxypyridine-2-carboxylic acid (0.031 g, 2.2 × 10-4 mol), and the complex [Ru(3-OH-py-2-COO)2(PPh3)2] (2) was synthesized by the reaction between [RuCl2(PPh3)3] (0.2 g, 2.0 × 10-4 mol) and 3-hydroxypyridine-2-carboxylic acid (0.061 g, 4.4 × 10-4 mol). The mixtures of the compounds were refluxed in methanol (60 mL) for 3 h. After this time, they were cooled and filtered. Crystals suitable for X-ray crystal analysis were obtained by slow evaporation of the reaction mixtures.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,19621-92-2, its application will become more common.
Reference:
Article; Ma?ecki; Krompiec; Maro?; Penkala; Polyhedron; vol. 48; 1; (2012); p. 21 – 30;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem