Application of 89488-29-9, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 89488-29-9, name is 2-Bromo-4-methoxypyridine. This compound has unique chemical properties. The synthetic route is as follows.
A Straus flask equipped with a stirrer bar was charged with 2-bromopyridine (1.0 equiv.), 1-naphthylboronic acid (1.1 equiv),Pd(PPh3)4 (4 mol%), 2 M aq Na2CO3 (2.5 mL/mmol), toluene(3.8 mL/mmol), and ethanol (1.3 mL/mmol). The mixture wasdegassed by three freeze-pump-thaw cycles and then refluxedunder inert conditions overnight. The mixture was cooled to r.t.and extracted with EtOAc (3 ¡Á 20 mL). The organic phases werecombined, dried (MgSO4), and concentrated. The pure ligandwas obtained by flash column chromatography [silica gel,EtOAc-hexane (1:4)].Compound was isolated as viscous liquid that solidified uponstanding. Yield: 1.6 g (99%).
According to the analysis of related databases, 89488-29-9, the application of this compound in the production field has become more and more popular.
Reference:
Article; Njogu, Rachael E.N.; Fodran, Peter; Tian, Yuxi; Njenga, Lydia W.; Kariuki, David K.; Yusuf, Amir O.; Scheblykin, Ivan; Wendt, Ola F.; Wallentin, Carl-Johan; Synlett; vol. 30; 7; (2019); p. 792 – 798;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem