Electric Literature of 6443-85-2, Adding some certain compound to certain chemical reactions, such as: 6443-85-2, name is 2-(Pyridin-3-yl)acetonitrile,molecular formula is C7H6N2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 6443-85-2.
EXAMPLE 8 (Z)-3-(9-Ethyl-9H-carbazol-3-yl)-2-(pyridin-3-yl) acrylonitrile 9-Ethyl-9H-carbazol-3-yl-carboxaldehyde (4.46 g; 0.02 mol) and 3-pyridylacetonitrile (2.36 g; 0.02 mol) were dissolved in ethanol (25 mL). Sodium methoxide (1 mL of 25% methanol solution) was added. The mixture was then left standing at ambient temperature for 24 hours. The formed precipitate was collected by filtration and dried to give 2.4 g (37% yield) of the title compound as a yellow solid, m.p. 131-133 C. Anal. Calcd. for C22 H17 N3: C, 81.71; H, 5.30; N, 12.99. Found: C, 81.38; H. 5.49; N, 12.84. Mass spectrum (EI; M+) m/z 323. 1 H-NMR (DMSO-d6; 400 MHz) delta 8.98 (d, 1H), 8.75 (d, 1H), 8.60 (dd, 1H), 8.28 (s, 1H)1, 8.18 (dd, 1H), 8.12-8.16 (m, 2H), 7.8 (d, 1H), 7.68 (d, 1H), 7.51-7.56 (m, 2H), 7.29 (t, 1H), 4.49 (q, 2H), and 1.34 ppm (t, 3H).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 6443-85-2, 2-(Pyridin-3-yl)acetonitrile, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; American Home Products Corporation; US5710164; (1998); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem