Related Products of 20511-12-0, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 20511-12-0, name is 5-Iodopyridin-2-amine. A new synthetic method of this compound is introduced below.
B. 2-Amino-5-(methylthio)pyridine A suspension of Cu powder (9.0 g), NaOMe (34.5 g, 0.638 mol), methylthiol (0.642 mol), and 2-amino-5-iodopyridine (100 g, 0.455 mol) in 800 ml of MeOH is heated in an autoclave at 150 C. for 12 hours. After cooling, the reaction mixture is filtered, and the filtrate is evaporated in vacuo. The residue is partitioned between EtOAc and H2 O. The organic layer is separated, washed with H2 O, dried and evaporated in vacuo. Recrystallization from MeOH yields the title compound.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,20511-12-0, its application will become more common.
Reference:
Patent; E. R. Squibb & Sons, Inc.; US4221796; (1980); A;,
Pyridine – Wikipedia,
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