Application of 504-29-0, Adding some certain compound to certain chemical reactions, such as: 504-29-0, name is Pyridin-2-amine,molecular formula is C5H6N2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 504-29-0.
2-Aminopyridine (4.7 g,50 mmol) was dissolved in a mixture of water (6 mL),glacial acetic acid (120 mL), and concentrated sulfuricacid (1 mL) preliminarily cooled to room temperature. Upon mixing, iodine (6 g, 23.6 mmol) and NaIO4(1.6 g, 7.5 mmol) were added. The mixture was kept at80C for 4 h, then 200 mL of 10% sodium thiosulfate solution was added and extracted with ethyl acetate(3 ¡Á 150 mL). The organic phase was washed with10% sodium hydroxide solution (3 ¡Á 60 mL) and brine(2 ¡Á 50 mL), dried over anhydrous Na2SO4, evaporated,and purified by flash chromatography (chloroform-ethanol, 50 : 1). Violet powder (10.3 g, 94%);1H NMR: 8.04 (d, J2 2.1, 1H), 7.58 (dd, J2 8.6, 2.2,1H), 6.35 (d, J2 8.6, 1H), 6.10 (br, 2H).
According to the analysis of related databases, 504-29-0, the application of this compound in the production field has become more and more popular.
Reference:
Article; Baleeva, N. S.; Baranov, M. S.; Smirnov, A. Yu.; Zaitseva, E. R.; Zaitseva, S. O.; Russian Journal of Bioorganic Chemistry; vol. 46; 1; (2020); p. 120 – 123; Bioorg. Khim.; vol. 46; 1; (2020); p. 120 – 123,4;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem