New downstream synthetic route of 6-(4-Isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-amine

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Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 1448427-99-3, name is 6-(4-Isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-amine. This compound has unique chemical properties. The synthetic route is as follows. COA of Formula: C10H13N5

Alternative Synthesis of Compound (A) Compound (E) (1 equiv.), Compound (C) (1 equiv.), DMF (about 16 vols), Et3N (1.5 equiv.), Pd(OAc)2(0.02 equiv.), and Ad2P(-Bu) (0.04 equiv.) were combined and the contents were purged with N2followed by CO and then pressurized with CO (20 psi). The reaction mixture was heated to about 95 C to about 105 C. After about 24 hours, the reaction was allowed to cool to about 20 C to about 30 C to afford Compound (A).

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 1448427-99-3, 6-(4-Isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-amine.

Reference:
Patent; GILEAD SCIENCES, INC.; BROWN, Brandon Heath; CHAN, Brenda J. Burke; CHIU, Anna; GRIGGS, Nolan; HEUMANN, Lars V.; LATHROP, Stephen P.; REYNOLDS, Troy Evan; SARMA, Keshab; SILER, David Allen; THOMPSON, Andrew S.; WANG, Tao; (146 pag.)WO2016/106384; (2016); A1;,
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