New downstream synthetic route of 6-(Hydroxymethyl)picolinonitrile

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 50501-38-7, 6-(Hydroxymethyl)picolinonitrile, other downstream synthetic routes, hurry up and to see.

Reference of 50501-38-7, Adding some certain compound to certain chemical reactions, such as: 50501-38-7, name is 6-(Hydroxymethyl)picolinonitrile,molecular formula is C7H6N2O, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 50501-38-7.

P4: For alternative syntheses, see [36?38]. The reaction was performed under nitrogen. SeO2 (386 mg, 3.48 mmol) and P3 (933 mg, 6.96 mmol) were stirred in dioxane (30 mL; neither dried nor degassed) at 110°C (bath temperature) for 24 h to give a dark yellow solution and black precipitate of selenium. The mixture was filtered through Celite to remove selenium. Celite was washed with CH2Cl2. Purification by chromatography (10 g of silica; CH2Cl2)gave pale yellow eluate of the product. White solid: 692 mg(5.24 mmol; 75percent; C7H4N2O; MW 132.12).

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 50501-38-7, 6-(Hydroxymethyl)picolinonitrile, other downstream synthetic routes, hurry up and to see.

Reference:
Article; Shavaleev, Nail M.; Eliseeva, Svetlana V.; Inorganica Chimica Acta; vol. 427; (2015); p. 81 – 86;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem