New downstream synthetic route of 7-Bromo-1H-pyrrolo[3,2-c]pyridine

At the same time, in my other blogs, there are other synthetic methods of this type of compound,902837-42-7, 7-Bromo-1H-pyrrolo[3,2-c]pyridine, and friends who are interested can also refer to it.

Adding a certain compound to certain chemical reactions, such as: 902837-42-7, 7-Bromo-1H-pyrrolo[3,2-c]pyridine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Recommanded Product: 902837-42-7, blongs to pyridine-derivatives compound. Recommanded Product: 902837-42-7

Production Example 46 To a mixture of 7-bromo-1H-pyrrolo[3,2-c]pyridine (0.16 g) and THF (6.0 mL) were added di-tert-butyl dicarbonate (0.26 g) and N,N-dimethyl-4-aminopyridine (0.010 g) at room temperature, followed by stirring at room temperature for 17 hours. The reaction mixture was concentrated under reduced pressure and the residue was purified by silica gel column chromatography (ethyl acetate/hexane=0 to 25%) to obtain tert-butyl 7-bromo-1H-pyrrolo[3,2-c]pyridine-1-carboxylate (0.22 g).

At the same time, in my other blogs, there are other synthetic methods of this type of compound,902837-42-7, 7-Bromo-1H-pyrrolo[3,2-c]pyridine, and friends who are interested can also refer to it.

Reference:
Patent; Astellas Pharma Inc.; EP2277858; (2011); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem