Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 562825-95-0, name is N-Ethyl-3-nitropyridin-4-amine. This compound has unique chemical properties. The synthetic route is as follows. Safety of N-Ethyl-3-nitropyridin-4-amine
A mixture consisting of ethyl (3-nitropyridin-4-yl) amine (11.76 g, 70 MMOL) in acetic acid (140 mL) with sodium acetate (28.7 g, 350 MMOL) and bromine (13.44 g, 84 MMOL) was stirred in a sealed flask at 100 C for 18 h. Most of the solvent was removed in vacuo and the residue partitioned between CH2CI2 and water and the aqueous layer basified with NAHCO3. The organic extract was washed with water then brine, dried (NA2SO4) and all volatiles removed in vacuo. The residue was chromatographed on silica gel eluted with ethyl acetate: hexane (2: 8) to afford the title compound (10.4 g, 60%). MS: (M+H) + = m/z 246.
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Reference:
Patent; SMITHKLINE BEECHAM CORPORATION; WO2005/11700; (2005); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem