Related Products of 1000025-07-9, Adding some certain compound to certain chemical reactions, such as: 1000025-07-9, name is Vadadustat,molecular formula is C14H11ClN2O4, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 1000025-07-9.
Ethanol (1 5mL) and nicotinamide (0.2g) were charged in a RBF at 25±5C and the contents were heated to 60-65C and stirred for 30 min at 60-65C. Methyl ethyl ketone (15mL) and Vadadustat (0.5g) were charged into the reaction mass at 60-65C. The reaction mass was stirred for 30 minutes at 60- 65C. The mass was then slowly cooled to 25±5C and maintained under stirring at 25±5C for 16 hours. The reaction mass was cooled to 0-5C and stirred for 2-3 hours. The product obtained was filtered, washed with methyl ethyl ketone (2 mL) and dried under vacuum for 3 hours at 40C. The solid obtained was identified as 1 :1 co-crystal of Vadadustat Nicotinamide. Yield: 0.45 g.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 1000025-07-9, Vadadustat, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; MYLAN LABORATORIES LIMITED; JETTI, Ramakoteswara Rao; PILLI, Narasimha Murty; PATHURI, Srinivasarao; GOLIVI, Ramamohana Rao; JAYACHANDRA, Sureshbabu; (36 pag.)WO2020/75199; (2020); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem