Electric Literature of 161558-45-8, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 161558-45-8, Name is 2-((4-Chlorophenyl)(piperidin-4-yloxy)methyl)pyridine 4-nitrobenzoate, SMILES is ClC1=CC=C(C(C2=NC=CC=C2)OC3CCNCC3)C=C1.O=C(O)C4=CC=C([N+]([O-])=O)C=C4, belongs to pyridine-derivatives compound. In a article, author is Baker, Blake J. M., introduce new discover of the category.
A sustainable and scalable multicomponent continuous flow process to access fused imidazoheterocycle pharmacophores
Described herein is a green, continuous flow process for the synthesis of various aminoimidazoheterocycles, through the Groebke-Blackburn-Bienayme reaction (GBBR). This multicomponent procedure combines aminoazines, aldehydes and isocyanides to generate a wide variety of medicinally privileged, aminated imidazoheterocycle architectures. This method is performed in ethanol, using only mineral acid rather than the standard metal-based catalysts typical to the field. These sustainability benefits have been demonstrated even on multigram scale, exemplifying the facile scalability of the procedure. The process also boasts shorter reaction times, wider scope robustness, and improved yields compared to the currently available methods, with no requirement for an aqueous work-up procedure, affording resulting scaffolds of notable relevance, to a range of medicinal targets of academic and industrial interest.
Electric Literature of 161558-45-8, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 161558-45-8.
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem