Electric Literature of 6945-67-1, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 6945-67-1, name is 2-Bromo-4-nitropyridine. This compound has unique chemical properties. The synthetic route is as follows.
To a solution of sodium (480mg, 21mmol) dissolved in 1-propanol (45mL), was added 2-bromo-4-nitropyridine [(3.2g, 19.2mmol), J. Med. Chem. 46(7), 1273-1276; 2003] and the mixture was heated at 95C for 2 hours. The solvent was then evaporated under reduced pressure and the residue was suspended in chloroform and filtered. The filtrate was washed with water, dried over magnesium sulfate, and concentrated in vacuo to give an oily residue. The residue was distilled and title product was obtained during a temperature range of 145-150C, as a solid in 58% yield, 2.67g. 1H-NMR(CDCl3, 400MHz) delta: 0.70(t, 3H), 1.58(m, 2H), 3.95(t, 2H), 6.65(m, 1H), 6.83(d, 1H), 8.02(d, 1H) Micro analysis found (%); C(44.10), H(4.70), N(6.80); C8H10BrNO requires (%); C(44.50), H(4.70), N(6.50)
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 6945-67-1, 2-Bromo-4-nitropyridine.
Reference:
Patent; Pfizer Limited; EP1595881; (2005); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem