Related Products of 189230-41-9, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 189230-41-9, name is 2-Bromopyridine-3,4-diamine. This compound has unique chemical properties. The synthetic route is as follows.
Step 2: To a solution of 2-fluoro-6-iodobenzaldehyde (1.5 g, 6.0 mmol) and 2-bromopyridine-3,4-diamine (1.1 g, 6.0 mmol) in ethanol (20 mL), was added ferric chloride (778 mg, 4.80 mmol). The reaction mixture was stirred at 60 C. under oxygen atmosphere overnight. The next day, solvent was evaporated via rotavap and theresulting residue was purified by column chromatography on silica gel eluting with petroleum/ethyl acetate (3:1) to give the desired product (1.6 g, 64% yield) as a yellow solid. LCMS (ESI) m/z: 418 [M+H+].
According to the analysis of related databases, 189230-41-9, the application of this compound in the production field has become more and more popular.
Reference:
Patent; GENENTECH, INC.; Lai, Yingjie; Liang, Jun; Magnuson, Steven R.; Robarge, Kirk D.; Tsui, Vickie H.; Zhang, Birong; US2014/206702; (2014); A1;,
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