The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 271-63-6, name is 1H-Pyrrolo[2,3-b]pyridine. This compound has unique chemical properties. The synthetic route is as follows. 271-63-6
General procedure: A solution of indole, azaindole or pyrrole (0.1 mmol) in dichloromethane (5 mL) was added to a suspension of 1:1 (W/W) ICl (concentration indicated in the Table; 0.1 mmol = 162 mg) and Celite (162 mg) ratio in dichloromethane (10 mL). The mixture was stirred at room temperature for the time indicated in Tables 1-4. The reaction mixture was then poured into saturated thiosulfate solution (20 mL) extracted with dichloromethane (2 x 15 mL). The organic layer was washed in brine and, dried over sodium sulfate and the solvent was removed at reduced pressure. The desired compound was purified by chromatography column using hexane and ethyl acetate mixtures as eluting solvent. Yields of iodinated compounds are summarized in Tables 1-4. All the compounds were characterized by IR, NMR and were compared with authentic samples.
Statistics shows that 271-63-6 is playing an increasingly important role. we look forward to future research findings about 1H-Pyrrolo[2,3-b]pyridine.
Reference:
Article; Hamri, Salha; Rodriguez, Jose; Basset, Joan; Guillaumet, Gerald; Dolors Pujol; Tetrahedron; vol. 68; 31; (2012); p. 6269 – 6275;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem