Related Products of 766-16-5, Adding some certain compound to certain chemical reactions, such as: 766-16-5, name is 4-Fluoro-2-methylpyridine,molecular formula is C6H6FN, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 766-16-5.
4-Fluoro-2-methylpyridine(4.32 g, 4.01 mL, 38.9 mmol), NBS (6 g, 33.7 mmol) and AIBN(0.56 g, 3.4 mmol) were mixed and CCl 4 (50 mL) was added, followed by heating to 80 C. for 3 h. After cooling the reaction mixture with diatomaceous earthThe filtrate was concentrated under reduced pressure and the crude product was purified by silica gel column chromatography (eluent: PE / EtOAc (v / v) = 9/1) to giveTo 1.3 g of product as a brown oil, yield: 16%.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 766-16-5, 4-Fluoro-2-methylpyridine, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Guangdong Dongyangguang Pharmaceutical Co., Ltd.; Liu Bing; Bai Shun; Zhou Youbo; Yang Tiping; He Wei; Zhang Yingjun; Zheng Changchun; (103 pag.)CN106749268; (2017); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem