The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 500-22-1, name is 3-Pyridinecarboxaldehyde. This compound has unique chemical properties. The synthetic route is as follows. SDS of cas: 500-22-1
General procedure: A mixture of bromine chloride resin and K2CO3 in MeOH-H2O (8:2) 3 mL was placed in a round-bottom flask fitted with amagnetic stirrer. To this, the aldehyde (1 mmol, 1 equiv) was added dropwise, and the reaction mixture stirred at r.t. The progress of the reaction was monitored by TLC. After completionof the reaction the mixture was filtered, and the filtrate was extracted with Et2O. The ether layer was washed with H2O, brine, dried over Na2SO4, filtered, and concentrated. The residue was purified by column chromatography, if required, over silicagel (60-120 mesh) using a mixture of PE and EtOAc (9:1) as eluent.
With the rapid development of chemical substances, we look forward to future research findings about 500-22-1.
Reference:
Article; Sridhar; Swarnalakshmi; Selvaraj; Synlett; vol. 27; 9; (2016); p. 1344 – 1348;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem