Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 5407-87-4, name is 2-Amino-4,6-dimethylpyridine. This compound has unique chemical properties. The synthetic route is as follows. 5407-87-4
Step 1 Preparation of 2-amino-4,6-dimethyl-5-bromopyridine 20 g(0.164 mole) of 2-amino-4, 6-dimethylpyridine was added into a mixture of 69 ml of water and 16.1 g(0.164 mole) of sulfuric acid and the resulting solution was cooled to 0 C., and thereto was added 8.45 ml(0.164 mole) of bromine gradually at 0 C. The resulting solution was stirred for 30 minutes, adjusted to pH 9 to 10 with aqueous sodium hydroxide solution and extracted with dichloromethane. The organic layer was washed with water, dried over anhydrous Na2 SO4 and concentrated under reduced pressure. The residue was purified with silica gel column chromatography to obtain 18.25 g of the title compound(yield 55%) and 5.4 g of dibromo compound(yield 11.8%).
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Reference:
Patent; Korea Research Institute of Chemical Technology; US5849753; (1998); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem