Adding a certain compound to certain chemical reactions, such as: 55589-47-4, 3-Methylpicolinaldehyde, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Recommanded Product: 3-Methylpicolinaldehyde, blongs to pyridine-derivatives compound. Recommanded Product: 3-Methylpicolinaldehyde
(7-(4-Methylpiperazin-1-yl)-1H-imidazo[4,5-b]pyridin-2-yl)methanamine (50 mg, 0.2 mmol) was dissolved in 2 mL of DCE (1,2-Di Chloroethane) 3-methyl-2-pyridinecarboxaldehyde (0.2 mmol, 24 mg) and NaBH(OAc)3 (64 mg, 0.3 mmol) were added and the mixture was stirred at room temperature for 2 h. Diluted with DCM and washed with saturated sodium bicarbonate and saturated brine, the organic layer was dried over anhydrous sodium sulfate, concentrated by filtration, and the residue was purified by column chromatography to give the title compound as a pale yellow gum (46percent yield).
At the same time, in my other blogs, there are other synthetic methods of this type of compound,55589-47-4, 3-Methylpicolinaldehyde, and friends who are interested can also refer to it.
Reference:
Patent; Chinese Academy Of Sciences Shanghai Pharmaceutical Institute; Long Yaqiu; Cao Bin; (103 pag.)CN103570683; (2018); B;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem