Adding a certain compound to certain chemical reactions, such as: 58602-02-1, 2,6-Difluoro-3-nitropyridine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 58602-02-1, blongs to pyridine-derivatives compound. name: 2,6-Difluoro-3-nitropyridine
Step A 2,6-difluoro-3-nitropyridine (14.68g,91.8mmol) was added to a mixture of DL-alanine ethyl ester hydrochloride (14.09g 92mmol) and potassium carbonate (25.3g, 183mmol) in acetonitrile (200ml) and the mixture stirred for 2 hours at room temperature. The reaction mixture was poured into water and extracted several times with ethyl acetate; the combined extracts were dried (MgSO4) and the solvent removed in vacuo leaving a viscous orange-yellow residue which solidified on standing. The solid was triturated with hexane and the solvent removed from the hexane soluble fraction leaving ethyl DL-2-[6-fluoro-3-nitropyridyl-2-amino]propionate as a yellow solid m.p. 49-51 C.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,58602-02-1, its application will become more common.
Reference:
Patent; Imperial Chemical Industries PLC; US5133798; (1992); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem