Electric Literature of 5350-93-6, Adding some certain compound to certain chemical reactions, such as: 5350-93-6, name is 6-Chloropyridin-3-amine,molecular formula is C5H5ClN2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 5350-93-6.
To 0.5 g (3.9 mmol) of 6-chloro-pyridin-3-ylamine in 6 mL of 12M HC1 at-20°C were added a solution of 0.36 g (5.2 mmol, 1. 3 eq) of sodium nitrite dissolved in 2 mL of H20. The reaction mixture was stirred for 15 min, and 4.4 g (19.5 mmol, 5 eq) of tin chloride dihydrate dissolved in 2 mL of 12M HC1 were added. The reaction mixture was allowed to reach 0°C within 40 min, and the white precipitate was recovered by filtration and washed with Et20 to yield 0.35 g (62percent) of (6-chloro-pyridin-3-yl) -hydrazine hydrochloride as a white solid, MS: 144 (MH+).
According to the analysis of related databases, 5350-93-6, the application of this compound in the production field has become more and more popular.
Reference:
Patent; F. HOFFMANN-LA ROCHE AG; WO2005/92856; (2005); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem