Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 695-34-1, Name is 4-Methylpyridin-2-amine, molecular formula is C6H8N2, belongs to pyridine-derivatives compound. In a document, author is Torralvo, Hector, introduce the new discover, SDS of cas: 695-34-1.
Pyridine- and Quinoline-Derived Imines as N,N-Bidentate Directing Groups in Palladium versus Platinum C-H Bond Activation Reactions
The C-H activation by Pd(II) and Pt(II) compounds of a wide range of imines related to 2-pyridinecarboxaldehyde, ArCH=NCH2(CH2)(n)Ph (Ar = 2-pyridinyl, 2-picolinyl, 2-quinolinyl, n = 0, 1), which can be useful for bond functionalization assisted by bidentate directing groups, has been studied. The results indicate that the presence of two methyl groups at the alpha-carbon, relative to the imine nitrogen atom, facilitates the metalation. The heterocyclic fragment of the chelating ligand also shows a relevant influence on the full process, the cyclometalated compounds being more easily formed for the 2-picolinyl than for the 2-quinolinyl derivatives, while for the 2-pyridinyl derivatives the reaction is less favored. These effects have been found to be determinant for both palladium and platinum compounds. The preparative results can be explained by a steric enhancement of the metalation process, the reaction being strongly favored when bulky substituents are located in the proximity (alpha-carbon) of the coordinating nitrogen atoms (with both palladium and platinum). Furthermore, surprisingly the formation of six-membered platinacycles is especially favored. The kinetico-mechanistic studies of the C-H activation reaction, on some equivalent Pd(II) and Pt(II) coordination complexes of the family, have shown that the nature of the d(8) metal center plays a determinant role in the reactivity observed. In this respect, the Pt(II) square-planar center has been found to be much more involved in the energetics of the reaction than the Pd(II) equivalent. The full process can be seen as a mechanistic continuum that goes from an electrophilic substitution (Pd(II) centers) to an oxidative addition/reductive elimination sequence (Pt(II) centers). The observation is directly associated with the fact that the Pt(II) center is prone to the existence of oxidatively added Pt(IV) hydrido complexes.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 695-34-1. SDS of cas: 695-34-1.
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem