Synthetic Route of 628-13-7, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 628-13-7, Name is Pyridinehydrochloride, SMILES is [H]Cl.C1=NC=CC=C1, belongs to pyridine-derivatives compound. In a article, author is Chinthaparthi, Radha Rani, introduce new discover of the category.
Green synthesis and anticancer activity of tetrahydrodipyrazolo[3,4-b:4 ‘,3 ‘-e]pyridines catalyzed by phospho sulfonic acid
Biologically portent/significant tetrahydrodipyrazolo[3,4-b:4 ‘,3 ‘-e]pyridines are synthesized by an efficient green synthesis of various aldehydes with 3-methyl-1H-pyrazol-5(4H)-one in ammonium acetate using phospho sulfonic acid as a solid catalyst under microwave-assisted interaction under solvent-free conditions at 70 degrees C. This methodology is easy to handle and get good to excellent yields. Later the potential in vitro antiproliferation of the titled compounds is evaluated. Among all the titled compounds, 4s and 4t showed the most potent anticancer potentiality on the used cancer cell lines of SK-BR-3 and HeLa (IC50 = 10.70 +/- 0.27 and 12.58 +/- 0.38, and 19.38 +/- 0.32 and 21.55 +/- 0.41 mu g/mL for SK-BR-3 cells lines and HeLa cells lines, respectively), which were comparable to the positive control.
Synthetic Route of 628-13-7, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 628-13-7.
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem