Nie, Xufeng; Zheng, Yanling; Ji, Li; Fu, Haiyan; Chen, Hua; Li, Ruixiang published the artcile< Acceptorless dehydrogenation of amines to nitriles catalyzed by N-heterocyclic carbene-nitrogen-phosphine chelated bimetallic ruthenium (II) complex>, Name: Pyridin-4-ylmethanamine, the main research area is heterocyclic carbene nitrogen phosphine chelate bimetallic ruthenium complex preparation; amine ruthenium complex catalyst dehydrogenation green chem; nitrile preparation.
A clean, atom-economical and environmentally friendly route for acceptorless dehydrogenation of amines to nitriles by combining a new dual N-heterocyclic carbene-nitrogen-phosphine ligand R(CNP)2 (R = o-xylyl) with a ruthenium precursor [RuCl2(η6-C6H6)]2 was developed. In this system, the electronic and steric factors of amines had a negligible influence on the reaction and a broad range of functional groups were well tolerated. All of the investigated amines was converted to nitriles in good yield of up to 99% with excellent selectivity. The unprecedented catalytic performance of this system was attributed to the synergistic effect of two ruthenium centers chelated by R(CNP)2 and a plausible reaction mechanism was proposed according to the active species found via in-situ NMR and HRMS.
Journal of Catalysis published new progress about Amines Role: RCT (Reactant), RACT (Reactant or Reagent). 3731-53-1 belongs to class pyridine-derivatives, and the molecular formula is C6H8N2, Name: Pyridin-4-ylmethanamine.