Nishiyama, Hisao; Yamaguchi, Shinobu; Park, Soon Bong; Itoh, Kenji published the artcile< New chiral bis(oxazolinyl)bipyridine ligand (bipymox): enantioselection in the asymmetric hydrosilylation of ketones>, Formula: C22H26N4O2, the main research area is asym hydrosilylation ketone rhodium complex catalyzed; bisoxazolinylbipyridine rhodium complex preparation catalyst hydrosilylation; stereoselective reduction ketone rhodium complex catalyzed; phenylethanol.
A homochiral chiral bis(oxazolinyl)bipyridine ligand I (bipymox) and its rhodium complex II were synthesized to examine the enantioselectivity in the asym. hydrosilylation of ketones in comparison to other chiral oxazoline ligands such as bis(oxazolinyl)pyridine III (pybox) and mono(oxazolinyl)pyridine IV (pymox). The bipymox-rhodium catalyst gave (S)-1-phenylethanol (90% enantiomeric excess) in the reduction of acetophenone with diphenylsilane, the same as the pybox-rhodium system but opposite to the pymox-rhodium system. The reduction of 4-tert-butylcyclohexanone is also described.
Tetrahedron: Asymmetry published new progress about Hydrosilylation catalysts. 147409-41-4 belongs to class pyridine-derivatives, and the molecular formula is C22H26N4O2, Formula: C22H26N4O2.