《One-Pot Regiodirected Annulations for the Rapid Synthesis of π-Extended Oligomers》 was written by Nitti, Andrea; Osw, Peshawa; Calcagno, Giuseppe; Botta, Chiara; Etkind, Samuel I.; Bianchi, Gabriele; Po, Riccardo; Swager, Timothy M.; Pasini, Dario. Recommanded Product: 128071-75-0 And the article was included in Organic Letters in 2020. The article conveys some information:
Synthesis of fused benzoheterocycles e.g. I [R = H, Me] and II [X = S, O, N-Me; R1 = H, CO2Me] via one-pot regiospecific palladium catalyzed direct arylation (DHA) and cross aldol condensation of ortho-bromoaldehydes and 3-thiopheneacetic acid was reported. Direct arylation of 2-octyldodecyl benzo[b]thienobenzothiophene-4-carboxylates with 4,7-dibromobenzo[c][1,2,5]thiadiazole using palladium catalyst afforded benzodithiophene-containing oligomers III [R2 = R3 = H, R4 = 2-octyldecyl] and IV [R5 = R5 = H, R7 = 2-octyldecyl]. Preparation of benzodithiophene-containing oligomers III [R2 = R3 = F, R4 = 2-octyldecyl ] and IV [R5 = R6 = F, R7 = 2-octyldecyl] was developed via palladium catalyzed Stille reaction of 2-octyldodecyl 2-(tributylstannyl)benzo[b]thienobenzothiophene-4-carboxylates with 4,7-dibromo-5,6-difluorobenzo[c][1,2,5]thiadiazole. In the experimental materials used by the author, we found 2-Bromonicotinaldehyde(cas: 128071-75-0Recommanded Product: 128071-75-0)
2-Bromonicotinaldehyde(cas: 128071-75-0) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Recommanded Product: 128071-75-0