Niu, Luyao published the artcileSynthesis, structure and anticancer activity of three platinum(II) complexes with 2-phenylpyridine derivatives, Category: pyridine-derivatives, the publication is Inorganic Chemistry Communications (2021), 108737, database is CAplus.
Three luminescent Pt(II) complexes, [Pt(5-NO2-ppy)(H-5-NO2-ppy)(Cl)] (1), [Pt(2-(2′,4′-dF)-ppy)(H-2-(2′,4′-dF)-ppy)(Cl)] (2), [Pt(2-(3′,5′-dF)-ppy)(H-2-(3′,5′-dF)-ppy)(Cl)] (3) with 2-phenyl-5-nitropyridyl (5-NO2-ppy), 2-(2,4-difluorophenyl)pyridine (2-(2′,4′-dF)-ppy) and 2-(3,5-difluorophenyl)pyridine(2-(3′,5′-dF)-ppy) were synthesized. FTIR spectroscopy, multinuclear NMR spectroscopy and single-crystal x-ray crystallog. were used to determine their structures. The UV-visible absorption and photoluminescence (PL) spectra of 1–3 were measured. 1–3 Displayed rich photophys. properties with the maximum emission wavelengths at 403-527 nm in the photoluminescence spectra, which demonstrated 1–3 have the potential to become the DNA luminescent probes in living cells. The anticancer activities of these complexes were tested in vitro by MTT assay against four tumor cell lines BGC823, MGC803 (human gastric cancer cell lines), HepG2 (human hepatocellular carcinoma), A549 (human non-small-cell lung cancer cell lines), HL-7702(human normal liver cell line). Moreover, 3 displayed highest cytotoxicity against human gastric cancer cell lines with the values of IC50 at 13.036-26.594μM.
Inorganic Chemistry Communications published new progress about 89076-64-2. 89076-64-2 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitro Compound,Benzene, name is 5-Nitro-2-phenylpyridine, and the molecular formula is C11H8N2O2, Category: pyridine-derivatives.
Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem