Novak, Michael published the artcileNitrenium ions from food-derived heterocyclic arylamine mutagens, Name: 5-Nitro-2-phenylpyridine, the publication is Journal of the American Chemical Society (1998), 120(7), 1643-1644, database is CAplus.
The pivalic acid esters I (X = N, Y = CH, R = H, Me; X = CH, Y = N, R = H), models for the ultimate mutagenic and carcinogenic metabolites of heterocyclic arylamines, undergo spontaneous uncatalyzed hydrolysis under physiol. pH conditions, but become unreactive under acidic conditions in which the pyridyl N atom is protonated. Kinetic comparisons with the biphenyl ester I (X = Y = CH, R = H) show that the limiting hydrolysis rate constant, k0, is reduced by substitution of an N atom for a C atom by ∼104 for an ortho substitution and ∼30 for a meta substitution. The hydrolysis rates of these esters are insensitive to added N3–, but this nucleophile has considerable effect on reaction products. These results are consistent with a mechanism in which rate-limiting N-O bond heterolysis yields a nitrenium ion that is competitively trapped by solvent and N3–. The selectivity ratios, kaz/ks, for the corresponding ions II (X ≠ Y) are ∼10-300-fold smaller than kaz/ks for the 4-biphenylylnitrenium ion, II (X = Y = CH).
Journal of the American Chemical Society published new progress about 89076-64-2. 89076-64-2 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitro Compound,Benzene, name is 5-Nitro-2-phenylpyridine, and the molecular formula is C11H8N2O2, Name: 5-Nitro-2-phenylpyridine.
Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem