Recently I am researching about CATALYZED DIRECT AMIDATION; HIGHLY EFFICIENT CATALYST; CARBOXYLIC-ACIDS; SUBSEQUENT DECORATION; AG NANOPARTICLES; AMIDE SYNTHESIS; GRAPHITE OXIDE; ALCOHOLS; MILD; DISPERSION, Saw an article supported by the University Grants commission- UGC-CAS; Green Technology. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Patel, KPP; Gayakwad, EM; Shankarling, GS. The CAS is 614-18-6. Through research, I have a further understanding and discovery of Ethyl nicotinate. Safety of Ethyl nicotinate
Herein, we report a graphene oxide (GO) catalyzed condensation of non-activated esters and amines, that can enable diverse amides to be synthesized from abundant ethyl esters forming only volatile alcohol as a by-product. GO accelerates ester to amide conversion in the absence of any additives, unlike other catalysts. A wide range of ester and amine substrates are screened to yield the respective amides in good to excellent yields. The improved catalytic activity can be ascribed to the oxygenated functionalities present on the graphene oxide surface which forms H-bonding with the reactants accelerating the reaction. Improved yields and a wide range of functional group tolerance are some of the important features of the developed protocol.
About Ethyl nicotinate, If you have any questions, you can contact Patel, KPP; Gayakwad, EM; Shankarling, GS or concate me.. Safety of Ethyl nicotinate
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem