Reference of 6969-71-7, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C¨CH bond functionalisation has revolutionised modern synthetic chemistry. 6969-71-7, Name is [1,2,4]Triazolo[4,3-a]pyridin-3(2H)-one, SMILES is O=C1NN=C2C=CC=CN21, belongs to pyridine-derivatives compound. In a article, author is Takao, Toshiro, introduce new discover of the category.
Diruthenium complexes having a partially hydrogenated bipyridine ligand: plausible mechanism for the dehydrogenative coupling of pyridines at a diruthenium site
The reactions of the diruthenium tetrahydrido complex, Cp*Ru(mu-H)(4)RuCp* (1) (Cp* = eta(5)-C5Me5), with pyridines were investigated in relation to the dehydrogenative coupling of 4-substituted pyridines. Complex 1 reacted with gamma-picoline to yield the bis(mu-pyridyl) complex, {Cp*Ru(mu-H)(mu-4-MeC5H3)}(2) (2a), with the elimination of dihydrogen. Complex 2a immediately reacted with the liberated dihydrogen to yield mu-eta(2)-dihydrobipyridine (dhbpy) complex 4avia C-C bond formation between the two pyridyl groups, in which one of the pyridine rings underwent partial hydrogenation. The X-ray structure of 4a shows that the dhbpy moiety adopts a mu-eta(2) coordination mode at the Ru-2 site. Complex 4a was reversibly converted to 5avia the elimination of dihydrogen in which the dhbpy moiety adopts a mu-eta(2):eta(2) mode. Although 5a was coordinatively saturated, 5a readily reacted with (BuNC)-Bu-t to yield 6a. This was owing to the ability of the dhbpy ligand changing its coordination mode between the mu-eta(2):eta(2) and mu-eta(2) modes. This also causes the dehydrogenation from the dhbpy ligand to yield mu-eta(2):eta(2)-bipyridine complex 7a at 140 degrees C. However, 7a was not shown to be an intermediate of the catalysis. The reaction of 1 with 1,10-phenanthroline afforded mu-eta(2)-phenanthroline complex 8 containing two hydrides, which can be a model compound for the bipyridine elimination from the Ru-2 site. Dynamic NMR studies suggested that 8 was isomerised to an unsaturated mu-N-heterocyclic carbene (NHC) complex. The unsaturated nature of the mu-NHC complex is likely responsible for the uptake of the third pyridine molecule to turn over the catalytic cycle.
Reference of 6969-71-7, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 6969-71-7.
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem