HPLC of Formula: C6H5NO. In 2020.0 CHEMMEDCHEM published article about MEPRIN-ALPHA; FETUIN-B; FERTILIZATION RATE; STRUCTURAL BASIS; PROTEIN in [Koerschgen, Hagen; Stoecker, Walter] Johannes Gutenberg Univ Mainz, Inst Mol Physiol Cell & Matrix Biol, Johann Joachim Becher Weg 7, D-55128 Mainz, Germany; [Jaeger, Christian; Tan, Kathrin; Buchholz, Mirko; Ramsbeck, Daniel] Fraunhofer Inst Cell Therapy & Immunol IZI, Dept Drug Design & Target Validat MWT, Bioctr, Weinbergweg 22, D-06120 Halle, Saale, Germany in 2020.0, Cited 27.0. The Name is 3-Pyridinecarboxaldehyde. Through research, I have a further understanding and discovery of 500-22-1.
Despite huge progress in hormonal therapy and improved in vitro fertilization methods, the success rates in infertility treatment are still limited. A recently discovered mechanism revealed the interplay between the plasma protein fetuin-B and the cortical granule-based proteinase ovastacin to be a novel key mechanism in the regulation of fertilization. Upon sperm-egg fusion, cleavage of a distinct zona pellucida component by ovastacin destroys the sperm receptor, enhances zona robustness, and eventually provides a definitive block against polyspermy. An untimely onset of this zona hardening prior to fertilization would consequently result in infertility. Physiologically, this process is controlled by fetuin-B, an endogenous ovastacin inhibitor. Here we aimed to discover small-molecule inhibitors of ovastacin that could mimic the effect of fetuin-B. These compounds could be useful lead structures for the development of specific ovastacin inhibitors that can be used in infertility treatment or in vino fertilization.
Welcome to talk about 500-22-1, If you have any questions, you can contact Korschgen, H; Jager, C; Tan, KT; Buchholz, M; Stocker, W; Ramsbeck, D or send Email.. HPLC of Formula: C6H5NO
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem