Safety of Methyl 5-bromopicolinateIn 2005 ,ãLigand creation via linking – a rapid and convenient method for construction of novel supported PyOX-ligandsã?appeared in Tetrahedron. The author of the article were Oila, Markku J.; Tois, Jan E.; Koskinen, Ari M. P.. The article conveys some information:
A novel, tyrosine-derived, supported amino alc. linker was synthesized and used for attachment of picolinic acid derivatives onto different supports. When the resin bound mol. was further activated, the PyOX-moiety could be constructed reliably in enantiopure form. Furthermore, an efficient Pd-catalyzed modification of a picolinic acid derivative is presented. In the experiment, the researchers used many compounds, for example, Methyl 5-bromopicolinate(cas: 29682-15-3Safety of Methyl 5-bromopicolinate)
Methyl 5-bromopicolinate(cas: 29682-15-3) belongs to pyridine. The basicity and metallophilic high donor number of these π-deficient systems has long favored them as ligands in metal catalysis. The last decade saw pyridine assume a stronger role as functional group for directed C–H oxidation/activation.Safety of Methyl 5-bromopicolinate