An article Grignard reagents-catalyzed hydroboration of aldehydes and ketones WOS:000526118900004 published article about SOLVENT-FREE HYDROBORATION; COMPLEXES SYNTHESES; MAGNESIUM in [Wang, Weifan; Lu, Kai; Qin, Yi; Xu, Li; Ma, Mengtao] Nanjing Forestry Univ, Coll Sci, Nanjing 210037, Peoples R China; [Yao, Weiwei; Yuan, Dandan] Nanjing Univ Chinese Med, Coll Pharm, Nanjing 210023, Peoples R China; [Pullarkat, Sumod A.] Nanyang Technol Univ, Sch Phys & Math Sci, Div Chem & Biol Chem, Singapore 637371, Singapore in 2020.0, Cited 43.0. The Name is 3-Pyridinecarboxaldehyde. Through research, I have a further understanding and discovery of 500-22-1. Application In Synthesis of 3-Pyridinecarboxaldehyde
Simple, commercially available Grignard reagents have been used as highly efficient precatalysts for the hydroboration of a wide range of aldehydes and ketones. The reaction employs very low catalyst loadings (aldehydes: 0.05 mol%, ketones: 0.5 mol%), and proceeds rapidly (aldehydes: 10 min, ketones: 20 min) under neat condition at room temperature. The Grignard reagent catalyst demonstrated good substrate scope, functional group tolerance, and high chemoselectivity in the carbonyl hydroboration. DFT calculations were performed to investigate the possible reaction mechanism. In contrast to the traditional stoichiometric use of Grignard reagents, this newly developed protocol provides a catalytic application of these reagents for molecular transformations. (C) 2020 Elsevier Ltd. All rights reserved.
About 3-Pyridinecarboxaldehyde, If you have any questions, you can contact Wang, WF; Lu, K; Qin, Y; Yao, WW; Yuan, DD; Pullarkat, SA; Xu, L; Ma, MT or concate me.. Application In Synthesis of 3-Pyridinecarboxaldehyde
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem