Cost Efficient Synthesis of Diaryl Ethers Catalyzed by CuI, Imidazolium Chloride and Cs2CO3 was written by Paul, Sudeep;Joy, Bony P.;Rajendran, Rajarajan;Gudimetla, Vittal B.. And the article was included in ChemistrySelect in 2019.HPLC of Formula: 4783-68-0 This article mentions the following:
Synthetically versatile imidazolium chlorides, especially 1,3-bis-(2,6-diisopropylphenyl)-imidazolium chloride (IPrHCl) along with copper (I) iodide and cesium carbonate, were found to be useful to form C-O bonds via O-arylation of phenols with aryl halides to afford diaryl ethers ArOAr1 [Ar = Ph, 4-MeC6H4, 4-ClC6H4, etc.; Ar1 = Ph, 4-MeOC6H4, 2-pyridyl, etc.]. In this catalysis, the metal:ligand (Cu:IPr) loading was optimized to 1.0 mol%, making it an inexpensive and a simple one pot catalytic route for synthesizing a variety of diaryl ethers. The catalytic cycle was probed by UV-Vis, FT-IR and HRMS techniques confirming involvement of a copper-imidazolium-carbonate complex. In the experiment, the researchers used many compounds, for example, 2-Phenoxypyridine (cas: 4783-68-0HPLC of Formula: 4783-68-0).
2-Phenoxypyridine (cas: 4783-68-0) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Pyridine derivatives are also useful as small-molecule α-helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.HPLC of Formula: 4783-68-0