Copper(I) Halide for Regioselective Ortho-Halogenation of Directed Arenes was written by Perumgani, Pullaiah C.;Parvathaneni, Sai Prathima;Surendra Babu, G. V.;Srinivas, K.;Mandapati, Mohan Rao. And the article was included in Catalysis Letters in 2018.Electric Literature of C12H11N This article mentions the following:
Described is a copper(I) mediated halogenation via direct C-H functionalization of arenes. The combination of Cu(I) halide and (diacetoxyiodo)benzene provides a robust system for halogenation of 2-arylpyridines. High regio- and mono-selectivity was achieved for chlorination, bromination, and iodination of arene C-H bonds. In the experiment, the researchers used many compounds, for example, 2-(m-Tolyl)pyridine (cas: 4373-61-9Electric Literature of C12H11N).
2-(m-Tolyl)pyridine (cas: 4373-61-9) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Electric Literature of C12H11N