Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, SDS of cas: 766-11-0, 766-11-0, Name is 5-Bromo-2-fluoropyridine, SMILES is FC1=NC=C(Br)C=C1, belongs to pyridine-derivatives compound. In a document, author is Reiersolmoen, Ann Christin, introduce the new discover.
Mechanism of Au(III)-Mediated Alkoxycyclization of a 1,6-Enyne
Gold-mediated homogeneous catalysis is a powerful tool for construction of valuable molecules and has lately received growing attention. Whereas Au(I)-catalyzed processes have become well established, those mediated by Au(III) have so far barely been explored, and their mechanistic understanding remains basic. Herein, we disclose the combined NMR spectroscopic, single-crystal X-ray crystallographic, and computational (DFT) investigation of the Au(III)-mediated alkoxycyclization of a 1,6-enyne in the presence of a bidentate pyridine-oxazoline ligand. The roles of the counterion, the solvent, and the type of Au(III) complex have been assessed. Au(III) is demonstrated to be the active catalyst in alkoxycyclization. Alkyne coordination to Au(III) involves decoordination of the pyridine nitrogen and is the rate-limiting step.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 766-11-0 is helpful to your research. SDS of cas: 766-11-0.
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem